US Patent Issued to H. Lee Moffitt Cancer Center, Research Institute on April 14 for "Enhancing anti-tumor response in melanoma cells with defective sting signaling" (Florida Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,621, issued on April 14, was assigned to H. Lee Moffitt Cancer Center (Tampa, Fla.) and Research Institute Inc. (Miami).

"Enhancing anti-tumor response in melanoma cells with defective sting signaling" was invented by James Mule (Odessa, Fla.), Rana Falahat (Tampa, Fla.) and Glen Barber (Miami).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is a method for enhancing antitumor T cell responses in subjects. The method involves administering to the subject in need thereof a composition comprising a demethylating agent in an amount effective to demethylate STING proteins in the tumor cells. This method is particularly useful in subjects...