US Patent Issued to Guardant Health on March 3 for "Genetic variant detection based on merged and unmerged reads" (California Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,567,492, issued on March 3, was assigned to Guardant Health Inc. (Palo Alto, Calif.).

"Genetic variant detection based on merged and unmerged reads" was invented by Darya Chudova (Los Altos, Calif.) and Mohammad Reza Mokhtari (San Lorenzo, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and systems for improving identification of nucleic acid variants by identifying genetic sequence reads having identical molecular barcodes and sequences among sequence reads from a nucleic acid sequencer, grouping the genetic reads into a family, and processing families comprising split reads to detect the variants in a sample of polynucleotide molecules."...