US Patent Issued to Guardant Health on April 14 for "Methods and applications of gene fusion detection in cell-free DNA analysis" (California Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,603,152, issued on April 14, was assigned to Guardant Health Inc. (Palo Alto, Calif.).

"Methods and applications of gene fusion detection in cell-free DNA analysis" was invented by Bahram Ghaffarzadeh Kermani (Los Altos, Calif.) and Mohammad Reza Mokhtari (San Lorenzo, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Systems and methods are disclosed for determining gene fusion by determining a fused read containing sequencing data of a portion of a fused chromosome DNA molecule; determining a predetermined point on the genome with least one mapped portion of the fused read clipped at the predetermined point (a breakpoint); identifying two mapped ...