ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,647, issued on Nov. 4, was assigned to Guangzhou Joyo Pharmatech Co. Ltd. (Guangzhou, China).
"Macrocyclic derivative and use thereof" was invented by Yang Zhang (Shanghai), Kai Zhou (Shanghai), Fen Jiang (Shanghai), Li Zhang (Shanghai), Xiao Liu (Shanghai), Zheng Wang (Shanghai), Kevin X. Chen (Shanghai), Jian Li (Shanghai) and Shuhui Chen (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure discloses a class of macrocyclic derivatives, and specifically discloses a compound shown in formula (VI), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof."
The patent was filed on March 3, 2025, under Applicati...