ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,412, issued on Dec. 16, was assigned to GUANGZHOU JOYO PHARMATECH Co. LTD. (Guangdong, China).

"Compound as highly selective ROS1 inhibitor and use thereof" was invented by Jianfei Wang (Shanghai), Guangwen Yang (Shanghai), Jikui Sun (Shanghai), Zhihua Ao (Shanghai), Peng Li (Shanghai), Yang Zhang (Shanghai), Qiu Li (Shanghai), Jian Li (Shanghai) and Shuhui Chen (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a class of compounds having a highly selective inhibition of ROS1, and the use thereof in the preparation of drugs for treating diseases related to abnormal ROS1 kinase expression. Specifically disclosed are compounds rep...