US Patent Issued to Global Cancer Technology on May 26 for "Tri-substituted aryl and heteroaryl derivatives as modulators of PI3-kinase and autophagy pathways" (California Inventors)

ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,450, issued on May 26, was assigned to Global Cancer Technology Inc. (San Diego).

"Tri-substituted aryl and heteroaryl derivatives as modulators of PI3-kinase and autophagy pathways" was invented by Emily M. Stocking (Encinitas, Calif.) and Wolfgang J. Wrasidlo (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to tri-substituted aryl and heteroaryl derivatives, pharmaceutical compositions containing them, and methods of using them, including methods for modulating autophagy or preventing, reversing, slowing or inhibiting the PI3K-AKT-MTOR pathway, and methods of treating diseases that are associated with ...