ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,466, issued on April 7, was assigned to GEVO INC. (Englewood, Colo.).
"NKR variants for increased production of isobutanol" was invented by Christopher Smith (Englewood, Colo.), Timothy Hanly (Englewood, Colo.) and Jeanne Benoit (Englewood, Colo.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to recombinant microorganisms comprising at least one nucleic acid molecule encoding a ketol-acid reductoisomerase (KARI) or modified NADH-dependent variant thereof, wherein said KARI is at least about 60% identical to SEQ ID NO: 2. In various aspects of the invention, the recombinant microorganisms may comprise an isobutanol produ...