ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,346, issued on April 7, was assigned to Georgia Tech Research Corp. (Atlanta) and University of Louisville Research Foundation Inc. (Louisville, Ky.).

"Crosslinked hydrogel for immune checkpoint blockade delivery" was invented by Andres J. Garcia (Atlanta), Maria M. Coronel (Atlanta), Haval Shirwan (Columbia, Mo.) and Esma S. Yolcu (Columbia, Mo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are PD-L1 presenting compositions. The compositions may be used to effect immunomodulation in a variety of contexts. The compositions may be used to decrease rates of transplant rejection, including pancreatic islet cell transplantation. The compositi...