ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,835, issued on Jan. 20, was assigned to Genzyme Corp. (Cambridge, Mass.).
"Methods for enhanced removal of impurities during protein a chromatography" was invented by Carl A. Beigie (Plainville, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods relating to the purification of a polypeptide comprising an Fc region (e.g., an antibody) via protein A chromatography; methods relating to the use of a wash solution comprising a benzoate salt and/or benzyl alcohol during protein A chromatography; and methods of adjusting a harvest using sodium benzoate prior to protein A chromatography."
The patent was filed on Dec. 17, 2021,...