ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,546,767, issued on Feb. 10, was assigned to GENOPSY Co. LTD. (Seoul, South Korea).
"Method for detection of unstable cell-free DNA and device using same" was invented by Youngnam Cho (Seoul, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "In an embodiment, the present invention relates to a technique in which small-sized cfDNA is detected, with ultrahigh sensitivity, from a liquid sample such as urine, cerebrospinal fluid, plasma, blood, pleural fluid, or body fluid, is concentrated and isolated, and then is analyzed for gene mutations without PCR. In particular, in a case where a positively charged nanostructure is used, capture and detectio...