ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,707, issued on Jan. 27, was assigned to GENOME BIOLOGICS UG (Frankfurt am Main, Germany).
"Method for generating cardiac tissue mimetics" was invented by Jaya Krishnan (Kronberg im Taunus, Germany), Minh Duc Pham (Offenbach, Germany) and Stefanie Dimmeler (Frankfurt am Main, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method for generating a cardiac tissue mimetic, comprising the steps of mixing cardiomyocytes (CM) and fibroblasts (FB) at a ratio from 2.5:1 to 10:1, thereby providing a first mixture, incubating said first mixture, such that said cardiomyocytes and said fibroblasts form a spherical structure, add...