US Patent Issued to Genentech on Sept. 8 for "Randomized configuration targeted integration of nucleic acids" (California Inventors)

ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,459, issued on Sept. 8, was assigned to Genentech Inc. (South San Francisco, Calif.).

"Randomized configuration targeted integration of nucleic acids" was invented by Shahram Misaghi (South San Francisco, Calif.) and Bradley R. Snedecor (South San Francisco, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The presently disclosed subject matter relates to "Randomized Configuration Targeted Integration" (also referred to herein as "Randomized Chain Targeted Integration") (RCTI) strategies for the generation and identification of host cells capable of expressing recombinant proteins, e.g., monoclonal antibodies, as well as compositions derived fr...