ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,936, issued on May 12, was assigned to GENEMEDICINE Co. LTD. (Seoul, South Korea).
"Anti-tumor composition" was invented by Chae Ok Yun (Seoul, South Korea) and Eon Ju Oh (Seoul, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an oncolytic adenovirus capable of co-expressing interleukin-12 and a C-met-inhibiting oligonucleotide; and an antitumor immune-boosting composition and anticancer composition comprising the oncolytic adenovirus. The present invention has first identified an adenovirus system having simultaneous effects of IL-12 expression and C-met inhibition in cancer gene treatment. The adenovirus ...