ALEXANDRIA, Va., June 16 -- United States Patent no. 12,653,886, issued on June 16, was assigned to Fred Hutchinson Cancer Center (Seattle).
"T-cell immunotherapy specific for WT-1" was invented by Thomas M. Schmitt (Seattle), Aude G. Chapuis (Seattle) and Philip D. Greenberg (Mercer Island, Wash.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides binding proteins specific for human Wilms tumor protein 1 (WT-1) epitopes, as well as host cells that express the binding proteins. Also provided are polynucleotides that encode a binding protein and vectors that comprise a polynucleotide. Related methods and uses of the presently disclosed compositions are provided for treating diseases...