US Patent Issued to Fred Hutchinson Cancer Center on Feb. 24 for "Antibody-based compositions for targeting tropomyosin receptor kinase B (TrkB) isoforms" (Washington Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,560, issued on Feb. 24, was assigned to Fred Hutchinson Cancer Center (Seattle).

"Antibody-based compositions for targeting tropomyosin receptor kinase B (TrkB) isoforms" was invented by Eric Holland (Seattle) and Siobhan Pattwell (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "In some aspects, the disclosure provides antibody-based reagents that specifically bind a tropomyosin receptor kinase B (TrkB) isoform that is associated with cancers. In some embodiments, the isoform is TrkB.T1. In some embodiments, the antibody or antibody derivative specifically binds a polypeptide comprising, consisting essentially of, or consisting of the sequenc...