ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,548, issued on July 28, was assigned to Foundation Medicine Inc. (Boston).
"BCOR rearrangements and uses thereof" was invented by Douglas I. Lin (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods related to detecting rearrangements in the B-cell lymphoma 6 (BCL6) corepressor (BCOR) or BCL6 corepressor-like protein I (BCORL1) gene, as well as methods of treatment, uses, and kits related thereto. As demonstrated herein, detection of BCOR rearrangements can be used to identify individuals that may benefit from treatment with a targeted therapeutic, such as a CDK inhibitor, an MDM2 inhibitor, a tyrosine kinase i...