ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,560, issued on March 17, was assigned to Fondazione Telethon (Rome) and Ospedale San Raffaele S.r.l. (Milan).
"Gene vector" was invented by Alessandra Biffi (Milan), Bernhard Rudolf Gentner (Milan) and Luigi Naldini (Milan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A gene vector for use in gene therapy comprising at least one miRNA sequence target operably linked to a nucleotide sequence having a corresponding miRNA in a hematopoietic progenitor cell (HSPC) or hematopoietic stem cell (HSC) which prevents or reduces expression of the nucleotide sequence in a HSPC or HSC but not in a differentiated cell."
The patent was filed on June 30, 2022, u...