US Patent Issued to FLAGSHIP PIONEERING INNOVATIONS VII on July 21 for "Therapeutic circular DNA forms" (Massachusetts Inventors)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,745, issued on July 21, was assigned to FLAGSHIP PIONEERING INNOVATIONS VII LLC (Cambridge, Mass.).

"Therapeutic circular DNA forms" was invented by Edward Matthew Kennedy (Bedford, Mass.), Camilo Ayala Breton (Andover, Mass.), Carl Wayne Brown III (Westborough, Mass.) and Brian Patrick Mead (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides, for example, double stranded DNA (dsDNA) molecules comprising one or more chemically modified nucleobases. In some embodiments, the dsDNA molecule is circular and comprises a first strand a second strand, wherein the first strand comprises one or more chemically modified nu...