US Patent Issued to FIVE PRIME THERAPEUTICS on March 31 for "CD80 extracellular domain Fc fusion proteins for treating PD-L1 negative tumors" (California Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,132, issued on March 31, was assigned to FIVE PRIME THERAPEUTICS INC. (Thousand Oaks, Calif.).

"CD80 extracellular domain Fc fusion proteins for treating PD-L1 negative tumors" was invented by Susannah D. Barbee (San Francisco), Thomas Brennan (Cupertino, Calif.) and Barbara Sennino (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of treating PD-L1 negative tumors, the methods comprising administering fusion proteins comprising the extracellular domain of human cluster of differentiation 80 (CD80) and the fragment crystallizable (Fc) domain of human immunoglobulin G 1 (IgG1)."

The patent was fil...