ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,463, issued on Feb. 10, was assigned to Five Eleven Pharma Inc. (Philadelphia).
"Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application" was invented by Zehui Wu (Philadelphia), Zhihao Zha (Philadelphia), Futao Liu (Philadelphia), Karl Ploessl (Wilmington, Del.), Seok Rye Choi (Aston, Pa.) and Hank F. Kung (Springfield, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to deuterated compounds according to Formula I-A, Formula II-A, Formula II-D, and Formula III-A. These compounds can be used as PET imaging agents for evaluating Parkinson's Disease, Alzheimer Diseas...