US Patent Issued to Fibrobiologics on Aug. 25 for "Treatment of disc degenerative disease and stimulation of proteoglycan synthesis by fibroblast conditioned media and formulations thereof" (California, Texas Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,716,055, issued on Aug. 25, was assigned to Fibrobiologics Inc. (Houston).

"Treatment of disc degenerative disease and stimulation of proteoglycan synthesis by fibroblast conditioned media and formulations thereof" was invented by Pete O'Heeron (Houston) and Thomas Ichim (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "In some aspects, disclosed are methods and compositions for disc regeneration and/or repair using one or more components from conditioned media from fibroblasts. In certain cases, conditioned media is obtained from fibroblasts stimulated with one or more opioid receptor antagonists and one or more toll-like receptor agonists. Con...