US Patent Issued to Evotec International on April 14 for "Modulators of the integrated stress response pathway" (British Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,720, issued on April 14, was assigned to Evotec International GmbH (Hamburg, Germany).

"Modulators of the integrated stress response pathway" was invented by Holly Victoria Atton (Oxfordshire, Great Britain) and Mohamad Sabbah (Oxfordshire, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, R4, R4a, R4b, R4c, R4d, R4e, R5, R6 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said com...