ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,916, issued on Jan. 20, was assigned to ETH ZURICH (Zurich).
"Transmembrane pH-gradient polymersomes" was invented by Jean-Christophe Leroux (Zurich), Simon Matoori (Zurich) and Olha Voznyuk Wuerthinger (Zurich).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides polymersomes comprising amphiphilic block-copolymers and their use to quantify ammonia in samples (e.g., body fluid samples). More particularly, it provides a polymersome comprising (a) a membrane, which comprises a block copolymer of poly(styrene) (PS) and poly(ethylene oxide) (PEO), wherein the PS/PEO molecular weight ratio is higher than 1.0 and lower than 4.0; a...