ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,691, issued on July 21, was assigned to ETERN BIOPHARMA (SHANGHAI) Co. LTD. (Shanghai).
"Crystalline form of SHP2 inhibitor, and composition thereof, preparation method therefor, and use thereof" was invented by Qiangang Zheng (Shanghai), Hao Zhuge (Shanghai) and Ye Zhao (Suzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present application relates to a compound 1 ((S)-1'-(8-((2-amino-3-chloropyridin-4-yl)thio)imidazo[1,2-c]pyrimidin-5-yl)-5,7-dihydrospiro[cyclopenta[b]pyridine-6,4'-piperidine]-5-amine) represented by formula (I), a novel crystalline form of a hydrate or a solvate thereof, and a pharmaceutical composition comprising t...