US Patent Issued to EPICYPHER on Nov. 4 for "DNA-barcoded nucleosomes for chromatin mapping assays" (North Carolina, Tennessee, Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,246, issued on Nov. 4, was assigned to EPICYPHER INC. (Durham, N.C.).

"DNA-barcoded nucleosomes for chromatin mapping assays" was invented by Martis W. Cowles (Chapel Hill, N.C.), Zu-Wen Sun (Brentwood, Tenn.), Michael-Christopher Keogh (Cambridge, Mass.), Bryan Jacob Venters (Cary, N.C.) and Ellen Nichole Weinzapfel (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to DNA-barcoded recombinant nucleosomes and polynucleosomes that have been engineered for use as spike-in controls for chromatin accessibility assays, chromatin mapping assays, e.g., using tethered enzymes, as well as other chromatin assays. The in...