ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,715,909, issued on Aug. 25, was assigned to ENTHERA S.R.L. (Milan).
"Inhibitors and uses thereof" was invented by Giovanni Amabile (Milan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to inhibitors of IGFBP5 and/or of at least one of its receptors, wherein said inhibitor has anti-fibrotic effect, methods for their production, pharmaceutical compositions containing said inhibitors, and uses thereof. In particular, the invention relates to antibodies or antigen binding fragments thereof that bind specifically to human IGFBP5 and/or to at least one of its receptors."
The patent was filed on Feb. 19, 2021, under Application N...