ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,270, issued on July 14, was assigned to Emanate Biomedical Inc. (Larchmont, N.Y.).

"Oral appliance for treating inflamed tissue of the oral cavity using the top-down method" was invented by Peter John Zegarelli (Sleepy Hollow, N.Y.) and Jarret Scott Fass (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "An oral appliance for delivering a medicament to an inflamed tissue inside an oral cavity is provided. The oral appliance has an interior surface configured to contour at least a portion of teeth and/or soft tissue areas inside the oral cavity, the interior surface of the oral appliance having a medicament disposed at a discrete region of the ...