ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,528, issued on Feb. 24, was assigned to EditForce Inc. (Fukuoka, Japan) and KYUSHU UNIVERSITY NATIONAL UNIVERSITY Corp. (Fukuoka, Japan).
"PPR protein causing less aggregation and use of the same" was invented by Yusuke Yagi (Fukuoka, Japan), Takayoshi Imai (Fukuoka, Japan), Takayuki Tamai (Fukuoka, Japan), Takahiro Nakamura (Fukuoka, Japan) and Takamasa Teramoto (Fukuoka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "In order to improve aggregation property of a PPR protein, the A6 amino acid of the 1st PPR motif from the N-terminus (M1) is made more hydrophilic. Further, the A9 amino acid of M1 is made to be a hydrophilic amino acid or glyc...