US Patent Issued to Duke University on Aug. 4 for "Thrombus imaging aptamers and methods of using same" (North Carolina Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,697,401, issued on Aug. 4, was assigned to Duke University (Durham, N.C.).

"Thrombus imaging aptamers and methods of using same" was invented by Bruce A. Sullenger (Durham, N.C.), Kady-Ann C. Steen-Burrell (Durham, N.C.) and Bethany Powell Gray (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are imaging agents, antidotes to the imaging agents and methods of using the same to image a thrombus or blood clot or thrombin including sites of thrombin accumulation and to diagnose and treat thrombosis. The imaging agents include an aptamer capable of binding the thrombus or thrombin in particular linked to a reporter moiety. The imag...