US Patent Issued to Drexel University on May 19 for "Substituted pyrrolo[1,2-aquinoxalin-4(5H)-ones as CX3CR1 antagonists" (American, Chinese Inventors)

ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,555, issued on May 19, was assigned to Drexel University (Philadelphia).

"Substituted pyrrolo[1,2-aquinoxalin-4(5H)-ones as CX3CR1 antagonists" was invented by Joseph M. Salvino (Chester Springs, Pa.), Xin Feng (Jiulongpo District, China), Alessandro Fatatis (Penn Valley, Pa.), Fei Shen (Collegeville, Pa.) and Olimpia Meucci (Penn Valley, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides compounds of Formula (I) having the structure:Compounds of Formula (I) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are furth...