ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,154, issued on March 24, was assigned to DNA Script (Le Kremlin-Bicetre, France).
"Template-free enzymatic synthesis of polynucleotides using poly(A) and poly(U) polymerases" was invented by Tillmann Heinisch (Le Kremlin-Bicetre, France), Elise Champion (Paris), Elodie Sune (Le Kremlin-Bicetre, France) and Mikhael Soskine (Franconville, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to methods and compositions for template-free enzymatic synthesis of a polyribonucleotide of a predetermined sequence from 3'-O-reversibly blocked nucleoside triphosphates using poly(A) and poly(U) polymerases."
The patent was f...