ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,186, issued on July 7, was assigned to DNA SCRIPT SAS (Le Kremlin-Bicetre, France).

"Efficient product cleavage in template-free enzymatic synthesis of polynucleotides" was invented by Sandrine Creton (Le Kremlin-Bicetre, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to methods and kits for template-free enzymatic synthesis of polynucleotides that include or enable a step of efficiently cleaving the polynucleotide products from its initiator using an endonuclease V activity and initiator with a 3'-penultimate deoxyinosine."

The patent was filed on Jan. 12, 2024, under Application No. 18/411,522.

*For furthe...