US Patent Issued to DIRECT BIOLOGICS on March 31 for "Methods and compositions for treating inflammatory conditions associated with infectious disease" (California, Colorado Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,310, issued on March 31, was assigned to DIRECT BIOLOGICS LLC (Austin, Texas).

"Methods and compositions for treating inflammatory conditions associated with infectious disease" was invented by Kenneth Allen Pettine (Fort Collins, Colo.), Kevin Hicok (San Diego) and Timothy Alexander Moseley (Fallbrook, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods of treating perianal fistula a subject by administering a therapeutic MSC secretome product made by a method comprising culturing bone marrow-derived MSCs under conditions that include oxygen tension below 5% and a culture media with a pH below 7."

The patent was filed on A...