US Patent Issued to DH Technologies Development on Oct. 27 for "Gain calibration for quantitation using on-demand/dynamic implementation of MS sensitivity improvement techniques" (Canadian Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,776,482, issued on Oct. 27, was assigned to DH Technologies Development Pte. Ltd. (Singapore).

"Gain calibration for quantitation using on-demand/dynamic implementation of MS sensitivity improvement techniques" was invented by Douglas Arnold Simmons (Whitby, Canada) and Wen Jin (Richmond Hill, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "Ions fragmented from a known precursor ion of a known compound are received by an ion guide that ejects the ions into an extraction region of a TOF mass analyzer. The ion guide ejects the ions using Zeno pulsing mode and the TOF mass analyzer measures intensities of the ions over time, producing a Zeno group of...