ALEXANDRIA, Va., June 16 -- United States Patent no. 12,653,838, issued on June 16, was assigned to Decibel Therapeutics Inc. (Boston).
"Methods of otoprotection against platinum-based antineoplastic agents" was invented by John Lee (Arlington, Mass.), John R. Soglia (Sherborn, Mass.), Qi-Ying Hu (Needham, Mass.) and Fuxin Shi (Winchester, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods for otoprotection against platinum-based antineoplastic agents by administering a thiosulfate salt to a subject in need thereof. Typically, the thiosulfate salt is administered to the subject scheduled to be administered a platinum-based antineoplastic agent within 4 hours. Alternatively, the...