ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,225, issued on Sept. 8, was assigned to Dana-Farber Cancer Institute Inc. (Boston).
"Non-canonical SWI/SNF complex and uses thereof" was invented by Cigall Kadoch (Tiburon, Calif.), Brittany C. Michel (Brookline, Mass.) and Andrew D'Avino (Boston).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compositions and methods for treating cancers with canonical BAF (cBAF) complex perturbations (e.g. synovial sarcoma or malignant rhabdoid tumor) using an agent that inhibits the formation, activity, and/or stability of the ncBAF complex."
The patent was filed on Oct. 15, 2019, under Application No. 17/283,797.
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