US Patent Issued to DANA-FARBER CANCER INSTITUTE on July 21 for "Arginine methyltransferase 5 (PRMT5) degraders and uses thereof" (Massachusetts, New Hampshire Inventors)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,776, issued on July 21, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Arginine methyltransferase 5 (PRMT5) degraders and uses thereof" was invented by Jun Qi (Sharon, Mass.), Lei Wu (Allston, Mass.), Paul M. Park (Waltham, Mass.) and Logan H. Sigua (North Sutton, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are to bifunctional compounds that target PRMT5 for degradation, compositions, and methods for treating diseases or conditions mediated by aberrant arginine methyltransferase 5 (PRMT5) activity."

The patent was filed on April 5, 2021, under Application No. 17/917,075.

*For further information, including images, c...