US Patent Issued to DANA-FARBER CANCER INSTITUTE on July 14 for "Compounds for targeted degradation of interleukin-2-inducible T-cell kinase and methods of use" (Massachusetts, California Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,678,508, issued on July 14, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Compounds for targeted degradation of interleukin-2-inducible T-cell kinase and methods of use" was invented by Nathanael S. Gray (Stanford, Calif.), Baishan Jiang (Watertown, Mass.), David Weinstock (Jamaica Plain, Mass.) and Wenchao Wu (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are bispecific compounds (degraders) that target ITK or a zinc finger (ZnF) protein for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat diseases and disorders characterized or me...