ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,666, issued on Dec. 16, was assigned to Daiichi Sankyo Co. Ltd. (Tokyo), Daiichi Sankyo Europe GmbH (Munich) and Amgen Inc. (Thousand Oaks, Calif.).

"Nucleic acid biomarker and use thereof" was invented by Matthias Schneider (Neufarn, Germany), Sabine Blum (Munich), Renee Jeanne Mendell-Harary (Skillman, N.J.), Daniel J. Freeman (Holmdel, N.J.), Robert Allen Beckman (Blue Bell, Pa.) and Xiaoping Jin (Hillsborough, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to methods of identifying and treating a human subject harboring a tumor or other disease comprising assessing HRG gene expression at an mRNA level in th...