US Patent Issued to CYTOMX THERAPEUTICS on July 14 for "Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof" (California, Colorado Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,899, issued on July 14, was assigned to CYTOMX THERAPEUTICS INC. (South San Francisco, Calif.).

"Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof" was invented by Stephen James Moore (Danville, Calif.), Margaret Thy Luu Nguyen (San Francisco), Daniel R. Hostetter (Rocklin, Calif.), Olga Vasiljeva (Highlands Ranch, Colo.) and Jeanne Grace Flandez (Benicia, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one matrix metalloprotease (MMP), to activatable antibodies and other larger molecules th...