ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,137, issued on March 31, was assigned to CITY OF HOPE (Duarte, Calif.).
"Meditope-enabled T cells" was invented by John C. Williams (Monrovia, Calif.), Christine Brown (Pasadena, Calif.), Kurt Jenkins (Duarte, Calif.), Yi-Chiu Kuo (Duarte, Calif.) and Cheng-Fu Kuo (Duarte, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compositions which exhibit novel therapeutic capabilities and allow to reduce the off-target effect of therapeutic antibodies. The compositions include recombinant proteins that if expressed by a T cell can efficiently recruit therapeutic antibodies to their site of action."
The patent was filed on Dec. 31...