US Patent Issued to CITY OF HOPE on Dec. 2 for "Substituted pyrazino[2,1-c[1,2,4triazines as Wnt/CBP/catenin signaling pathway inhibitors" (California Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,275, issued on Dec. 2, was assigned to CITY OF HOPE (Duarte, Calif.).

"Substituted pyrazino[2,1-c[1,2,4triazines as Wnt/CBP/catenin signaling pathway inhibitors" was invented by Michael Kahn (Monrovia, Calif.) and David Horne (Altadena, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed and provided herein are, inter alia, compounds of formula (Ia), (Ib), or (Ic):or pharmaceutically acceptable salts or stereoisomers thereof, and use thereof in methods for modulating CREB binding protein (CBP)/catenin signaling pathway activity and treating CBP/Beta-catenin mediated disorders."

The patent was filed on March 11, 2021, under Application No...