US Patent Issued to Chugai Seiyaku on May 12 for "Antigen-binding molecule for promoting disappearance of antigen via FcGammaRIIB" (Japanese Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,089, issued on May 12, was assigned to Chugai Seiyaku K.K. (Tokyo).

"Antigen-binding molecule for promoting disappearance of antigen via FcGammaRIIB" was invented by Tomoyuki Igawa (Shizuoka, Japan), Atsuhiko Maeda (Shizuoka, Japan), Yuki Iwayanagi (Shizuoka, Japan), Kenta Haraya (Shizuoka, Japan), Hitoshi Katada (Shizuoka, Japan), Shojiro Kadono (Kanagawa, Japan) and Futa Mimoto (Shizuoka, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides antigen-binding molecules containing (i) an antigen-binding domain whose antigen-binding activity varies depending on ion concentration conditions, (ii) an FcGammaR-binding domain ...