ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,594, issued on March 3, was assigned to Chugai Seiyaku K.K. (Tokyo).

"Pharmaceutical composition containing 9-ethyl-6, 6-dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6, 11-dihydro-5H-benzo[bcarbazole-3-carbonitrile" was invented by Akira Kitayama (Tokyo) and Takeshi Sasoh (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention aims to provide a high-dose formulation with improved properties of a pharmaceutical composition comprising a poorly soluble basic agent, particularly a compound represented by formula (I) or a salt thereof. The problem described above can be solved by providing a pharmaceutical composition comprisin...