US Patent Issued to Children's Medical Center on May 26 for "Compositions and methods for generating physiological X chromosome inactivation" (Massachusetts Inventors)

ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,697, issued on May 26, was assigned to Children's Medical Center Corp. (Boston).

"Compositions and methods for generating physiological X chromosome inactivation" was invented by Yi Zhang (Boston) and Azusa Inoue (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features compositions and methods for recapitulating physiological X-chromosome inactivation (XCI) in a cell, including a cell of any embryo generated by Somatic Cell Nuclear Transfer (SCNT). In one aspect, the invention features a method for generating physiological X chromosome inactivation in an embryo generated by SCNT, the method comprising injecting the embryo...