US Patent Issued to CHECKMATE PHARMACEUTICALS on July 28 for "Synthetic RIG-I-like receptor agonists" (Massachusetts Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,133, issued on July 28, was assigned to CHECKMATE PHARMACEUTICALS INC. (Cambridge, Mass.).

"Synthetic RIG-I-like receptor agonists" was invented by Arthur M. Krieg (Cambridge, Mass.), Aaron Jay Morris (Brighton, Mass.) and Evan David Walters (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to, inter alia, RNA molecules (e.g., RNA hairpin agonists) that bind to and agonize RIG-I-like receptors (RLRs), and to use of the molecules, including RLR agonists packaged in vims like particles (VLPs), in methods for treating, or ameliorating one or more symptoms of, a disorder (e.g., cancer)."

The patent was file...