ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,219, issued on Sept. 8, was assigned to CHANGZHOU SYNTHEALL PHARMACEUTICALS Co. LTD. (Changzhou, China) and SHANGHAI STA PHARMACEUTICAL R&D Co. LTD. (Shanghai).
"Processes for preparing oligonucleotides" was invented by Chenchen Hu (Shanghai), Qiang Zhao (Changzhou, China), Qing Li (Changzhou, China) and Jimin Yang (Changzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are processes for preparing oligonucleotides. The process comprises: (a) converting a compound of Formula X-1 into a compound of Formula X-2: where R10 is a residue of an oligonucleotide (e.g., a phosphorodiamidate morpholino oligomer); R11 is an amine protecting g...