ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,851, issued on July 21, was assigned to CENTRAL SOUTH UNIVERSITY (Changsha, China).

"Optimized method for expansion and large-scale production of regulatory t cells (Tregs)" was invented by Haibo Yu (Changsha, China) and Zhiguang Zhou (Changsha, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "An optimized method for expansion and large-scale production of regulatory T cells (Tregs) includes the following steps: preparing a cord blood-derived Treg-containing suspension; transferring the cord blood-derived Treg-containing suspension into a sterile tube matching with a magnetic pole, and magnetically sorting CD4+CD25+CD127- Tregs out; adding an ex...