US Patent Issued to CENTESSA PHARMACEUTICALS (UK) on Dec. 23 for "Bicyclic-heterocycle derivatives and their uses as orexin-2 receptor agonists" (British, American Inventors)

ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,475, issued on Dec. 23, was assigned to CENTESSA PHARMACEUTICALS (UK) Ltd. (Altrincham, Great Britain).

"Bicyclic-heterocycle derivatives and their uses as orexin-2 receptor agonists" was invented by Bruce Lefker (Swampscott, Mass.), Karl Gibson (Sandwich, Great Britain), Matthew Spendiff (Cambridge, Great Britain), Paul Humphries (Santa Clara, Calif.), Sarah Bucknell (Cambridge, Great Britain), Wojciech Zawodny (Cambridge, Great Britain) and Roderick Alan Porter (Hertfordshire, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compounds of Formula (I'):and to their prodrugs, pharmaceutically acceptable s...