ALEXANDRIA, Va., March 24 -- United States Patent no. 12,582,706, issued on March 24, was assigned to Cell4Cure AB (Solna, Sweden).
"Tolerogenic antigen presenting cells" was invented by Lieneke Pool (Lund, Sweden), Pavlos Englezou (Lund, Sweden), Maria Wigren (Lund, Sweden) and Hanne Romedahl (Lund, Sweden).
According to the abstract* released by the U.S. Patent & Trademark Office: "There is provided inter alia according to the invention an ex vivo method of obtaining tolerogenic antigen presenting cells (APCs) that have the capability to induce tolerance in the immune system to an antigen, the method comprising (a) isolating monocytes from a sample obtained from a mammal; and (b) culturing the isolated monocytes in a cell culture to ind...